Red Cell Profile
Highly specialized cell responsible for
oxygen and carbon dioxide transport.
Highly specialized cell responsible for oxygen and carbon dioxide transport.
RBC Membrane
ØShape - biconcave disc
É40% lipids
É52% protein
É8% carbohydrate
ØPrimary physiologic functions
Éfacilitates O2-CO2 transport
ÐBlood buffer
ÐWaste disposal
ÉMaintain deformability
ÉKeeper of surface antigens
ØProteins
Éperipheral
Ðalpha & beta spectrin
×bands 1 & 2
Ðactin
Éintegral (lots of sialic acid)
Ðglycophorin A
Ðband 3
×inorganic anion transport channel
×cation pump regulates Na+/K+ at ratios 1:12/25:1
ØLipids
Éphospholipids
Ðlipid bilayer
Éunesterified cholesterol
Ðfacilitates selective cation permeability
Ð1:1 equilibrium w/plasma cholesterol
